Paediatric consent

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Assent, consent and paediatric bioethics

In the ethics of relations between physicians and paediatric patients the question of autonomy and its corollary, consent, is crucial. While the importance attached to autonomy in the clinical setting is not the same as that accorded in research, it nonetheless assumes greater relevance when minors are involved, and a careful case-by-case assessment becomes obligatory. In a book published in 19...

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Informed consent & ethical issues in paediatric psychopharmacology.

Issues relating to informed consent and ethics in paediatric psychopharmacology limit research in this population. Children vary in their levels of cognitive development, and presence of psychiatric disorder may further impair their ability to give informed consent. In decisional impairment subjects, various methods used for consent are assent/dissent; inclusion of advance directives; and/or al...

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Consent and assent in paediatric research in low-income settings

BACKGROUND In order to involve children in the decision-making process about participation in medical research it is widely recommended that the child's assent be sought in addition to parental consent. However, the concept of assent is fraught with difficulties, resulting in confusion among researchers and ethics committees alike. DISCUSSION In this paper, we outline the current internationa...

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Informed consent for paediatric clinical trials in Europe

OBJECTIVE Paediatric clinical trials are often conducted as multinational trials. Informed consent or assent is part of the ethics committee approval for clinical trials. The consent requirements vary between countries due to national laws and regulations, which are not harmonised in Europe. These discrepancies can present challenges for paediatric clinical trials. The aim of this study was to ...

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Informed consent in paediatric critical care research – a South African perspective

BACKGROUND Medical care of critically ill and injured infants and children globally should be based on best research evidence to ensure safe, efficacious treatment. In South Africa and other low and middle-income countries, research is needed to optimise care and ensure rational, equitable allocation of scare paediatric critical care resources. Ethical oversight is essential for safe, appropria...

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ژورنال

عنوان ژورنال: British Dental Journal

سال: 2007

ISSN: 0007-0610,1476-5373

DOI: 10.1038/bdj.2007.1125